@article{Hiller:Huse:Szafranski:Wides_occur_alter:2004,
author = {Hiller, Michael and Huse, Klaus and Szafranski, Karol and 
          Jahn, Niels and Hampe, Jochen and Schreiber, Stefan and 
          Backofen, Rolf and Platzer, Matthias},
title = {{Widespread} occurrence of alternative splicing at {NAGNAG} 
         acceptors contributes to proteome plasticity},
journal = {Nat Genet},
year = {2004},
doi = {10.1038/ng1469},
volume = {36},
user = {hiller},
publists = {All and Michael Hiller and Rolf Backofen},
pmid = {15516930},
pages = {1255-7},
number = {12},
issn = {1061-4036},
annote = {bioinformatics},
abstract = {Splice acceptors with the genomic NAGNAG motif may cause 
            NAG insertion-deletions in transcripts, occur in 30% of 
            human genes and are functional in at least 5% of human 
            genes. We found five significant biases indicating that 
            their distribution is nonrandom and that they are 
            evolutionarily conserved and tissue-specific. Because of 
            their subtle effects on mRNA and protein structures, these 
            splice acceptors are often overlooked or underestimated, but 
            they may have a great impact on biology and disease.}
}