EMBIO: Emergent Organisation in Complex Biomolecular Systems
Project description
Biomolecular systems exhibit spontaneous self-organisation that is critical to their function.
Examples are protein folding and the self-assembly of membranes. The project aims to develop
mathematical and computational approaches primarily to identify the poorly understood
principles of this phenomenon. This will provide a basis for modelling of this fundamental
property of complex biomolecular systems and will therefore be of great importance to biology,
medicine and biotechnology.
The project is funded by the European Commision in the Sixth Framework programme
within "New and emerging science and technology NEST - PATHFINDER" research area.
The consortium consists of eight Universities from six countries and coordinated by
Cambridge University.
Project web site
http://www-embio.ch.cam.ac.uk/
Funded and Associated Group Members
Main Publications
- Martin Mann, Cameron Smith, Mohamad
Rabbath, Marlien Edwards, Sebastian Will,
and Rolf Backofen.
CPSP-web-tool : a server for 3D lattice protein studies.
In Bioinformatics, 2009.
- Martin Mann, Daniel Maticzka, Rhodri Saunders, and Rolf Backofen.
Classifying protein-like sequences in arbitrary lattice protein models using LatPack.
In HFSP Journal, Special issue on protein folding , 2008.
Supplementary data can be obtained HERE .
- Martin Mann, Sebastian Will and Rolf Backofen.
CPSP-tools - Exact and Complete Algorithms for High-throughput 3D Lattice Protein Studies.
In BMC Bioinformatics, 9, 230, 2008.
- Sebastian Will and Martin Mann.
Counting protein structures by dfs with dynamic
decomposition.
In Proc. of the Workshop on Constraint Based Methods for
Bioinformatics, page 6, 2006.
- Michael T. Wolfinger,
Sebastian Will, Ivo L. Hofacker, Rolf Backofen, and Peter F. Stadler.
Exploring the lower part of discrete polymer model energy
landscapes.
Europhysics Letters, 2006.
Related Research Topics